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Physical exercise has been proposed as an adjunct in addiction treatment, including tobacco cigarette smoking. The physiological and biochemical mechanisms that could be affected by physical exercise in smokers and that could help quit smoking have not been investigated yet. To investigate whether the effects of acute exercise on smoking behavior and HPA axis activation in smokers are intensity-dependent. Healthy, non-systematically exercising individuals [25 smokers (age 33±1.4 years) and 10 non-smokers (age 34±2.1 years)] underwent th
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