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The descriptions from this study indicate that the parasite drastically compromises the host's respiratory system. Additionally, it is worth noting that parasite fauna studies of fishes in the Capim river are still a vast topic for research; this is the first record of infection by Henneguya sp. in Metynnis hypsauchen, captured in the Capim river in Ipixuna do Pará. © Indian Society for Parasitology 2019.Nile tilapia is an exotic species produced in Brazilian aquaculture. The aim of this study was to constitute a pathological diagnosis in