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It has been controversial whether to adjust for current body weight while examining the relationship between birthweight and blood pressure (BP). The present study aims to partition the total effect of birthweight on BP into its direct effect and indirect effect through current body mass index (BMI). The study cohort consisted of 6251 participants who had birthweight information with 13 443 observations on BMI and BP in pre-adolescence (4-11 years), adolescence (12-19 years), young adulthood (20-30 years) and mid-adulthood (31-58 years