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014). The results indicated that measuring platelet aggregation can be helpful in the early detection, diagnosis, and treatment of bleeding disorders.Three-color electrophoretic displays (EPDs) have the advantages of multi-color display and low power consumption. However, their red particles have the disadvantage of long response time. In this paper, a driving waveform, which is based on electrophoresis theory and reference gray scale optimization, was proposed to shorten the response time of red particles in three-color EPDs. The drivin