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At the end of the tenth week of oral administration, the blood glucose of the experimental group was significantly lower than that of the control group after intraperitoneal injection of glucose. By the twelfth week, fasting blood glucose level and fasting insulin level were measured in all mice, the results showed that the recombinant spores increased the insulin sensitivity of mice. Conclusions The results of pathological observation showed that the recombinant spores also had a certain protective effect on the liver and islets of mic