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The study aims to determine the thoughts, feelings and attitudes of nurses towards organisational change in hospitals, and the effects of organisational cynicism, job satisfaction, organisational commitment and work alienation on nurses' attitudes towards change. Changes and employees' thoughts, attitudes and behaviours can be mutually affected in the process of transformation. The descriptive, correlative and cross-sectional study was conducted with 1,000 nurses in 52 public hospitals in Turkey. Of the nurses, 59% explained that thei