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3% vs 29.7%, P=0.91. But the 28-day mortality of heparin users were lower than nonusers In patients with SIC score ≥4 (40.0% vs 64.2%, P=0.029), or D-dimer 6 fold of upper limit of normal (32.8% vs 52.4%, P=0.017). CONCLUSIONS Anticoagulant therapy mainly with LMWH appears to be associated with better prognosis in severe COVID-19 patients meeting SIC criteria or with markedly elevated D-dimer. This article is protected by copyright. All rights reserved.In the past decade, multiple catalytic C-H bond functionalization has been su