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The timing of discharge of COVID-19 patients should be determined by comprehensive analysis of CT images and RT-PCR test results. Primary carcinoma ex pleomorphic adenoma arising from the tracheobronchial system is rarely reported. We present a patient with primary carcinoma ex pleomorphic adenoma of the bronchus and review the associated literature for further comparison, including age, clinical manifestations, and diagnostic process. This patient had no history of neoplasms of the salivary gland. Positron emission tomography played a