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LTx from chosen donors ≥70 years is possible and safe, producing comparable short- and long-term outcome in a propensity-matched evaluation with more youthful donors ( less then 70 y).We demonstrate an economical alternative employing the fragment-based molecular tailoring strategy (MTA) for creating the potential energy surface (PES) for two dipeptides viz. alanine-alanine and alanine-proline using correlated principle, with augmented Dunning basis sets. About 1369