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A series prepared MxOy/HZSM-5 catalysts possesses standard crystal framework, huge specific area, pore amount, aperture also strong acidity. An efficient substitution of seleno-group on polysaccharide backbone is promoted by managing the acid web site of solid acids (Se content up to 15,170.49 μg/g) in contrast to the conventional Se-functionalization technique (1703 μg/g). Powerful Lewis and Brønsted acid web sites lead to the driving causes toward low molecular mass polysaccharide fragments, never