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In the microbiological assays the disc diffusion methods are still in the majority. The spectrophotometric methods were based in the UV-Vis region using buffer solutions as a diluent. All these methods can become greener, following green analytical chemistry principles, which could bring benefits both to the environment and the operator, and reduce costs. In this paper, a literature review regarding analytical methods for determination of vancomycin was carried out with a suggestion of greener alternatives. In this paper, a literature r
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