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Besides PEEP [control 5.0 (0., intervention 5.8 (1.1) cmH2O, p less then 0.001], the respiratory and hemodynamic variables were comparable between the two groups. The compliance profile analysis showed no significant differences between the two groups. The loss of ventral and dorsal regional ventilation was higher in the control [ventral 41.0 (16.3)%; dorsal 25.9 (13.8)%] than in the intervention group [ventral 29.3 (17.6)%; dorsal 16.4 (12.7)%; p (ventral) = 0.039, p (dorsal) = 0.028]. CONCLUSIONS Unfavorable compliance profiles indica