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The purpose of this study was to present the proton beam characteristics of the first clinical single-room ProBeam Compact™ proton therapy system (SRPT) and comparison against multi-room ProBeam™ system (MRPT). A newly designed SRPT with proton beam energies ranging from 70 to 220MeV was commissioned in late 2019. Integrated depth doses (IDDs) were scanned using 81.6mm diameter Bragg peak chambers and normalized by outputs at 15mm WET and 1.1 RBE offset, following the methodology of TRS 398. The in-air beam spot profiles were acquired