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Among the 265 patients just who underwent preliminary surgery, categorized according to immunohistochemistry, patients with DNA polymerase epsilon exonuclease domain mutation had a fantastic prognosis (RFS and OS), clients without any specific molecular profile (NSMP) and mismatch restoration protein deficiency had an advanced prognosis, and the ones with necessary protein 53 unusual expression (p53abn) had the worst prognosis (P 0.001). Within the NSMP team, mutant KRAS and wild-type ARID1A were