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ar disease, acute cardiac injury and heart failure were more common in deceased patients. CONCLUSION Severe acute respiratory syndrome coronavirus 2 infection can cause both pulmonary and systemic inflammation, leading to multi-organ dysfunction in patients at high risk. Acute respiratory distress syndrome and respiratory failure, sepsis, acute cardiac injury, and heart failure were the most common critical complications during exacerbation of covid-19. © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commerc