https://www.selleckchem.com/pr....oducts/Methazolaston
FTO was downregulated in prostate cancer tissues and cell lines, and the m A content was increased. Importantly, patients with lower FTO expression had advanced tumor stage and higher Gleason scores. Gain- and loss-of-function assays revealed that FTO inhibits prostate cancer cell invasion and migration in vitro. Moreover, we confirmed that FTO can decrease the total m A level. The present study revealed that the FTO m A demethylase inhibits prostate cancer cell invasion and migration by regulating total m A levels. The present s