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Abdominal aortic atherosclerotic plaque burden may have clinical significance but manual measurement is time-consuming and impractical. To perform external validation on an automated atherosclerotic plaque detector for noncontrast and postcontrast abdominal CT. The training data consisted of 114 noncontrast CT scans and 23 postcontrast CT urography scans. The testing data set consisted of 922 CT colonography (CTC) scans, and 1207 paired noncontrast and postcontrast CT scans from renal donors from a second institution. Reference standard d