https://www.selleckchem.com/pr....oducts/tbk1-IKKe-in-
NEO212 is a novel small-molecule anticancer agent that was generated by covalent conjugation of the natural monoterpene perillyl alcohol (POH) to the alkylating agent temozolomide (TMZ). It is undergoing preclinical development as a therapeutic for brain-localized malignancies. The aim of this study was to characterize metabolism and pharmacokinetic (PK) properties of NEO212 in preclinical models. We used mass spectrometry (MS) and modified high-performance liquid chromatography to identify and quantitate NEO212 and its
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