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Baculovirus particle contamination additionally hinders the purification of particulate services and products. In this research, a novel baculovirus vector of deficient-lef5 (Ac-Δlef5) ended up being set up to prevent the production of baculovirus particles. It may transduce cells and replicate viral DNA however the expression for the belated and incredibly belated genes ended up being reduced in order that no virus ended up being packed and budded. The Ac-Δlef5 expression sy