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Our conclusions exhibited SME may increase the aging‑related brain and liver harm through the Nrf2‑HO‑1 pathway.Neurodegenerative problems (NDD) are chronic neurological diseases characterized by loss and/or damage to neurons together with the myelin sheath, and patients are at higher risk of extreme infection because of the SARS‑CoV‑2. A comprehensive literature search was carried out utilizing relevant terms and inclusion‑exclusion criteria. Present articles, topics
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