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Genetic analysis of the polymorphism of the studied genes was carried out using real-time polymerase chain reaction (real-time PCR). The study did not find patterns in the distribution of homo- and heterozygous genotypes of A6986G polymorphic markers of the gene, 6 CT intron of the gene and rs6190 of the gene in patients with endocrine ophthalmopathy and their effect on the glucocorticoid response ( 0.05). Results of pharmacogenetic testing of the gene for the glucocorticoid receptor NR3C1 and cytochrome P450 do not provide a rel