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Epileptiform spike incidence correlated with microglial cell density and neuronal loss in the ipsilateral hippocampus. Epileptiform activity is frequent in the acute period of TBI period and is associated with distant hippocampal damage on a microscopic level. This damage is probably involved in late consequences of TBI. The FPI model is suitable for exploring pathogenetic mechanisms of post-traumatic disorders. Epileptiform activity is frequent in the acute period of TBI period and is associated with distant hippocampal damage on a mi