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Abbreviations ANOVA Analysis of variance; 5-ASA 5-aminosalicylic acid; Bax Bcl-2-associated X protein; COX-2 Cyclooxygenase-2; DAI Disease Activity Index; DMSO Dimethyl sulfoxide; GAPDH Glyceraldehyde 3-phosphate dehydrogenase; GSH Glutathione; HP Hydroxyproline; IAEC International Animal Ethics Committee; IBD Inflammatory Bowel Disease; IBS Inflammatory Bowel Syndrome; IL's Interleukin's; IFN-γ Interferon-gamma; IκBα nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-alpha; iNOs Inducible nitric oxide synthase