https://www.selleckchem.com/products/dcz0415.html
Optogenetics uses light to manipulate protein localization or activity from subcellular to supra-cellular level with unprecedented spatiotemporal resolution. We used it to control the activity of the Cdc42 Rho GTPase, a major regulator of actin polymerization and cell polarity. In this chapter, we describe how to trigger and guide cell migration using optogenetics as a way to mimic EMT in an artificial yet highly controllable fashion.The epithelial-mesenchymal transition (EMT) and the corresponding reverse process, mesenchymal-epithelia
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