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We illustrate the proposed method using synthetic data and two Nano-CT imaging datasets of Jiulaodong (JLD) shale and Longmaxi (LMX) shale acquired in the Sichuan Basin. These numerical experiments show that the proposed method substantially outperforms selected alternatives both visually and quantitatively.This study aimed to analyze the association between serum zinc levels and major subjective symptoms in zinc deficiency patients with chronic liver disease. 578 patients with chronic liver disease were enrolled. The patients, whose