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s of the number and quality of the included studies, further verification is required through the multi-center, large sample-sized, and high-quality RCTs in the future. To investigate the relationships of cancer antigen (CA) 125, CA 19-9, prothrombin time (PT), activated partial thromboplastin time (aPTT), thrombin time (TT), fibrinogen (FI, and D-dimer values with ovarian endometriosis (OEM), and to explore the validation of biomarkers for noninvasive preoperative evaluation of patients with severe OEM. This retrospective case-contro