https://www.selleckchem.com/pr....oducts/Cyclopamine.h
Increasing evidence shows that microRNA-7a-5p (miR-7a-5p) plays an important role in regulating the inflammatory process in inflammatory bowel disease (IBD). How miR-7a-5p contributes to this process is poorly defined. The purpose of this study was to examine whether miR-7a-5p regulates 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced inflammatory responses via the JNK pathway. Colitis was induced in male mice by intracolonic administration of TNBS; mice were divided into 3 groups normal control (NC), TNBS, and miR-7a-5p antagomir
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