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Here we review fundamental knowledge on this bacterium and discuss future directions of studies on its applications to electro-biotechnology (E. Tetracyclines are a group of broad-spectrum antibiotics that used to controls bacterial diseases in humans or are applied as feed additives to enhance growth in farm animals. Tetracyclines are released into the aquatic environment in different pathways. Many analytical methods combined with a preconcentration step have been introduced for the determination of tetracycline in various environment