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Our findings thus suggest that NSAIDs not only inhibit nociception but also prevent the progression of osteolysis in chronic and repeated attacks of GA. © 2020 THE AUTHORS. Published by Elsevier BV on behalf of Cairo University.Prevention is essential to reduce Colorectal Cancer (CRC) mortality. We previously reported a panel of four genes CEACAM6, LGALS4, TSPAN8, COL1A2 (CELTiC) able to discriminate patients with CRC. Here, we assessed the CELTiC panel by quantitative polymerase chain reaction, in the blood of 174 healthy subjects, who r