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71; P=.02). In nested models, CCL20 added value (χ =79.22; P.001) to a model already incorporating the Psoriasis Area and Severity Index, Framingham risk, high-sensitivity C-reactive protein, Il-17A, and IL-6 (χ =48.18; P.001) in predicting vascular endothelial inflammation. Our study was observational and did not allow for causal inference in the relationship between CCL20 and cardiovascular risk. We demonstrate that CCL20 expression has a strong association with vascular endothelial inflammation, reflects systemic inflammation, and may serve as a