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3. After risperidone treatment of 12weeks, rs3924999 and rs35753505 showed significant association with change in DVT and in RSPM in which there were significant differences among different genotype groups. This study suggested pharmacogenetic relationships between NRG1 variants and changes in cognition response with exposure to 12weeks of treatment with risperidone. Two variants, rs3924999 and rs35753505, in the NRG1 gene were associated with the changes in attention and reasoning ability after risperidone treatment of 12weeks. This st