https://www.selleckchem.com/pr....oducts/tp0427736-hcl
Sheep are highly adequate models for human renal diseases because of their many similarities in the histology and physiology of kidney and pathogenesis of kidney diseases. However, the lack of a simple method to measure glomerular filtration rate (GFR) limits its use as a model of renal diseases. Hence, we aimed to develop a simple method to measure GFR based on the plasma clearance of iohexol by assessing different pharmacokinetic models (a) CL2 two-compartment (samples from 15 to 420 min; reference method); (b) CL1 one-compartme
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