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The rapid development in healthcare technologies in recent years has resulted in the need for health services, whether publicly funded or insurance based, to identify means to maximise the benefits and provide equitable distribution of limited resources. This has resulted in the need for rationing decisions, and there has been considerable debate regarding the substantive and procedural ethical principles that promote distributive justice when making such decisions. In this paper, I argue that while the scientifically rigorous approach

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describe the core competencies of gerontological nurse specialists and investigate the factors that contribute to the development of core competencies. A descriptive cross-sectional study was conducted from August 2015-March 2016. The descriptive study of gerontological nurse specialists' core competencies used a self-assessment instrument with three first-level domains (attitude, skill and knowledge) and 9s-level dimensions. A total of 225 gerontological nurse specialists from ten provinces in China were selected by a convenience sampl

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PAGln thus represents a new CVD-promoting gut microbiota-dependent metabolite that signals via adrenergic receptors. Early life environmental exposure, particularly during perinatal period, can have a life-long impact on organismal development and physiology. The biological rationale for this phenomenon is to promote physiological adaptations to the anticipated environment based on early life experience. However, perinatal exposure to adverse environments can also be associated with adult-onset disorders. Multiple environmental stressors

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