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Despite chemotherapy being a common treatment, an increase in chemoresistance over time is unavoidable. We therefore investigated the role of miR-194-5p in regulating chordoma cell behavior and examined the downstream effectors of miR-194-5p. In this study, NSCLC cell lines A549 and H460 were cultured under hypoxic conditions for 1 week to induce drug resistance to doxorubicin (DOX). The connection between miR-194-5p and HIF-1 was revealed by reverse transcription and real-time polymerase chain reaction (RT-qPCR), western blot, and dual

https://www.selleckchem.com/pr....oducts/ferrostatin-1
Multi-date remotely sensed images comprising Landsat TM images of 1984, 1993 and 2003 and, Landsat OLI images of 2013 were used to reconstruct long-term changes in land cover in the Swartkops River Estuary by mapping changes in vegetation distribution over a period of ~ 30 years between 1984 and 2013. These images were complemented by high-resolution near-anniversary aerial photographs that were used as ancillary sources of ground truth during supervised classification of the Landsat images. Results of our investigation point to h

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users. Assessment of seed germination is an essential task for seed researchers to measure the quality and performance of seeds. Usually, seed assessments are done manually, which is a cumbersome, time consuming and error-prone process. Classical image analyses methods are not well suited for large-scale germination experiments, because they often rely on manual adjustments of color-based thresholds. We here propose a machine learning approach using modern artificial neural networks with region proposals for accurate seed germination dete

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Squamous cell carcinoma is the most common variant of anal malignancy. Certain disease-related factors have been established in determining survival. These include tumour size, differentiation and nodal involvement. Other factors such as HIV status, human papillomavirus infection, smoking and socioeconomic disparity may have important roles, however few data are available on the UK population. We aim to correlate social deprivation and survival of anal cancer patients at a tertiary centre. All consecutive cases diagnosed with anal squam

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Ti sei mai chiesto in che modo la traduzione può impattare il tuo messaggio? La traduzione su internet garantisce velocità, ma è veramente sempre accurata? Al contrario, la traduzione offline potrebbe apparire più affidabile. Qual è il significato reale di tutto ciò per te? Con Aqueduct Translations, ottieni il massimo da entrambe le realtà. I nostri servizi su misura uniscono la tecnologia all'esperienza dei linguisti professionisti. Non lasciare niente al destino; opta per una traduzione che risuoni davvero co

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Endothelial dysfunction, evaluated by flow-mediated dilatation (FMD), predicts adverse cardiovascular events in patients with intermittent claudication (IC). IC is an example of repeated ischemia/reperfusion injury that may contribute to the progression of vascular disease by worsening endothelial function, a trigger for acute cardiovascular events. The predictive value of effort-induced endothelial dysfunction for cardiovascular events in patients with IC has not been studied previously. The objective of this study was to assess wheth

https://www.selleckchem.com/pr....oducts/etanercept.ht
It is essential to go beyond individual behavior and tackle group decision-making at the farm level. This study found a positive effect of organizational participation in joint pest and disease control mechanisms. Moreover, whether the farm is situated in the demonstration zone for kiwifruit cultivation, planting experience, planting area, whether there are people in the family who are village cadres, and the number of older adults in the family significantly positively affect the degree of pest and disease control. © 2020 Society of

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76), or 30-day readmission rates (1.1% vs. 3.5%, p = 0.34). CONCLUSION In patients who underwent TVH, prior CS increased postoperative blood transfusion but did not increase risk for overall perioperative complications. The present study was conducted to explore the influence of dietary carbohydrate on antioxidant capacity and non-specific immunity of hybrid grouper, which would contribute to determine the tolerable dietary carbohydrate content. Seven diets with grade levels of carbohydrate (5.27, 8.95, 11.49, 14.37, 17.78, 20.82 and 23.

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nt and Shape Concern scores than transgender women; higher Eating, Weight, and Shape Concern scores than presumed cisgender men; and lower Restraint but higher Shape Concern scores than presumed cisgender women. These norms can help clinicians in treating this population and interpreting the EDE-Q scores of their gender-expansive patients. Gender-expansive individuals reported lower Restraint and Shape Concern scores than transgender women; higher Eating, Weight, and Shape Concern scores than presumed cisgender men; and lower Restraint