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67bpm; p=.002, adjusted p=.001), and this difference was most pronounced during night hours of 10PM to 5AM (61 vs. 67bpm; p.001). In the pilot analysis of the available PSG data, the release of obstructive sleep apneas and hypopneas coincided with fluctuation of HR. SDB is independently associated with higher mean HR in patients with HCM, and this difference is most significant during sleep. Treatment of SDB, which is readily available, should be tested as a complementary modality to the currently recommended pharmacotherapy aimed
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