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All four rotator cuff tendons from fresh human cadaver shoulders underwent biomechanical, histopathological, and gene expression analyses. Following cadaver supply, samples were grouped into Younger (i.e., less than 36 years of age, letter = 2 donors) and Aged (for example., greater than 55 several years of age, n = 3 donors) as a method of characterizing and quantifying the age-related modifications exhibited by the tendons. Biomechanical evaluating and subsequent computational m