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Moreover, NiPT could induce more lung cancer cells undergoing apoptosis if it synergistically uses autophagy inhibitors, suggesting that NiPT-induced autophagy protects cancer cell from death. Collectively, our findings demonstrate that autophagy inhibition enhances the anticancer effects of proteasomal DUB inhibitor and might be an effective treatment strategy for lung cancer. Copyright © 2020 Chen, Chen, Xu, Yang, Yang, Yang, Yan, Zhang, Feng and Liu.Background The detection rate for pulmonary nodules, particularly subsolid nodules (S
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