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Nonetheless, an external database was used to validate the prognostic genes from the TCGA. Prognostic genes were listed according to their expression position and protein function. We provided a new targets for immunotherapy of LUAD, which further provides basic knowledge for future clinical research. We provided a new targets for immunotherapy of LUAD, which further provides basic knowledge for future clinical research.SARS-CoV-2, a positive single-stranded RNA enveloped coronavirus, currently poses a global health threat. Drugs wit