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006, -0.001) and the inverse relation was more pronounced in male infants. In addition, PM2.5 level in the 2nd trimester was negatively related to activetone score (β, -0.012; 95% CI, -0.021, -0.002) in a dose-dependent manner for both genders. Collectively, our results demonstrated that prenatal exposure to PM2.5 was linked to poor neurobehavioral performance of newborns. The second trimester was the most sensitive time window for the developments of behavior and activetone, and male subject was more vulnerable as compared to females. An