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Hyaluronic Acid-based Bioinks
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Hyaluronic acid (HA) is the simplest glycosaminoglycan (a class of negatively charged polysaccharides) and is a major component of the extracellular matrix (ECM). HA is a linear, nonsulfated polysaccharide that provides compressive strength, lubricity and hydration within the ECM. It also regulates cell adhesion and mobility and can also mediate cell proliferation and differentiation, making it not only a structural component of tissues but also an active signaling molecule.