https://mek-signaling.com/inde....x.php/examining-your
Connexin (Cx) 46 is predominately expressed in lens fibre cells, where they work in maintaining the homeostasis and transparency regarding the lens. Cx46 mutations are involving disability of station function, which results in the development of congenital cataracts. Cx46 gap junctions and hemichannels are closely controlled by multiple systems. Key regulators of Cx46 channel function feature Ca2+ and calmodulin (CaM). Ca2+ plays an essential role in lens homeostasis, and i
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