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P. aeruginosa 5399 clinical strain shows low sensitivity to Norfloxacin in all tested micelle systems. The results suggest that Cremophor EL-Pluronic F127 mixed micelles can be considered as novel controlled release delivery systems for hydrophobic antimicrobial drugs.Advanced oxidation processes (AOPs) based on peroxydisulfate (PDS) or peroxymonosulfate (PMS) activation have attracted much research attention in the last decade for the degradation of recalcitrant organic contaminants. Sulfate (SO4•-) and hydroxyl (•OH) radicals are most