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Multivariate analysis showed that a median testosterone ≥50ng/dL was significantly associated with a decrease in bDFS (HR 6.58, 95%CI 1.28-33.76, p=0.03). Time to testosterone recovery after ADT did not correlate with bDFS, MFS, or OS and was not significantly associated with any of the testosterone subgroups. Our results do not support the concept that additional serum testosterone suppression below 20ng/dL is associated with better outcomes than 20-49ng/dL. Time to testosterone recovery after ADT and HRT did not impact clinical failur