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080, 95%CI 0.592-1.567, p less then 0.001). Obvious heterogeneity across studies was found in the study. Further analysis demonstrated that a significant difference in favor of the MOOC-based teaching method compared with the traditional teaching method in medical students and doctors. The MOOC-based teaching method may be applicable to medical education in China, strengthening the roles of MOOCs in medical education.Phosphorus limitation on terrestrial plant growth is being incorporated into Earth system models. The global pattern