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Positive associations were found between the number of confirmed cases of COVID-19 and CO, PM2.5, relative humidity, and O3, with and without MSI-adjustment. Negative associations were also found for SO2 and wind velocity both with and without controlling for population migration. In addition, air pollutants and meteorological factors had interactive effects on COVID-19 after controlling for MSI. In conclusion, air pollutants, meteorological factors, and their interactions all affect COVID-19 cases.Bean curd dreg (BCD) is a by