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95, 95% CI [-1.76, -0.13], =0.02), HCT (MD = -2.37, 95% CI [-3.25, -1.50], 0.00001), FIB (MD = -0.44, 95% CI [-0.60, -0.29], 0.00001), and PAR (OR = -7.65, 95% CI [-10.16, -5.14], 0.00001). However, no notable contrast was observed to link the experimental and the control team for PV (MD = -0.42, 95% CI [-0.83, 0.00], =0.05) and adverse reactions (OR = 0.59, 95% CI [0.13, 2.74], =0.5. Despite the limitations that existed in this meta-analysis, the outcomes demonstrated that SFI and conventional combined medication is an e