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The human activity introduces strong environmental stresses, and results in great spatiotemporal heterogeneity for the environment. Although the effects of environmental factors on the microbial diversity and succession have been widely studied, knowledge about how keystone taxa respond to environmental stresses remains poorly understood. We examined bacterial and archaeal communities from 45 wetland ponds covering a wide range of waters in Hangzhou. We found that shifts in bacterial and archaeal communities were strongly correlated wit