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The present review is designed to summarize the molecular mechanisms pertaining to the neuroprotective effects of curcumin and its nanoformulations. © 2020 Wiley Periodicals, Inc.OBJECTIVE This study sought to describe the clinical and laboratory procedures and to discuss aspects involved in obtaining satisfactory aesthetics on substrates presenting different colors. CLINICAL CONSIDERATIONS This case report describes the clinical and laboratory procedures for obtaining an optimal esthetic result using different ceramic framework materials