https://www.selleckchem.com/pr....oducts/gsk591-epz015
Taken together, NVD-BM was identified as a tumor suppressor in malignant melanoma, and we established a dual-input biosensor to promote cancer cell regression, via Akt1/NF-κB signaling. Our results demonstrate the potential therapeutic effects of cholesterol 7-desaturase in melanoma metabolism, and provides insights for genetic circuits targeting 7-dehydrocholesterol accumulation in tumors. In an ageing society, community-based medical education in a home care setting needs to be developed. Drawing on Kolb's experien