https://www.selleckchem.com/pr....oducts/dubs-in-1.htm
BACKGROUND Previous studies have shown that microRNAs (miRNAs) play important roles in the pathogenesis of human cancers. This study aims to clarify the role of miR-374b in non-small cell lung cancer (NSCLC). METHODS In this study, RT-qPCR and western blot analysis were used to measure mRNA and protein expression. The regulatory mechanism of miR-374b/ITGB1 was investigated by dual-luciferase reporter, CCK-8, and transwell assays. RESULTS MiR-374b expression was reduced in NSCLC tissues and associated with lymph node metastasis, tumor